chloroform 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4363 67-66-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chloroform
  • trichloroform
  • trichloromethane
A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
  • Molecular weight: 119.37
  • Formula: CHCl3
  • CLOGP: 1.95
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -1.23
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N01AB02 NERVOUS SYSTEM
ANESTHETICS
ANESTHETICS, GENERAL
Halogenated hydrocarbons
MeSH PA D012997 Solvents
CHEBI has role CHEBI:35470 central nervous system agents
CHEBI has role CHEBI:38870 inhalation anesthetics
CHEBI has role CHEBI:50903 carcinogen
CHEBI has role CHEBI:78433 refrigerants

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4025221 VUID
N0000171757 NUI
4025221 VANDF
C0008238 UMLSCUI
CHEBI:35255 CHEBI
MCH PDB_CHEM_ID
CHEMBL44618 ChEMBL_ID
DB11387 DRUGBANK_ID
2503 IUPHAR_LIGAND_ID
7V31YC746X UNII
6212 PUBCHEM_CID
1362698 RXNORM
NOCODE MMSL
001343 NDDF
001396 NDDF
259153006 SNOMEDCT_US
424273005 SNOMEDCT_US
D002725 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None